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Influence of Stroke on the Composition of Intestinal Microbiota

NCT02008604 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 24

Last updated 2018-11-29

No results posted yet for this study

Summary

The aim of the study is to verify the hypothesis that the microbial colonisation of the gut is changed in patients after stroke and that the gut microbiome of severely affected stroke patients differs from that of patients with only a short disruption of blood circulation in the brain (transient ischemic attack, TIA). For this, the composition of gut microbiota in stool samples will be analyzed by 454 pyrosequencing. Further, the correlation of stroke-associated changes in the microbiome with immunological parameters will be analyzed.

Conditions

  • Stroke
  • Transient Ischemic Attack (TIA)

Sponsors & Collaborators

  • Prof. Dr. Ulrich Dirnagl, Experimental Neurology, Charité Berlin, Germany

    collaborator UNKNOWN

  • Dr. Christian Meisel, Medical Immunology, Charité Berlin, Germany

    collaborator UNKNOWN

  • PD Dr. Andreas Nitsche, Robert-Koch-Institut, Berlin, Germany

    collaborator UNKNOWN

  • NeuroCure Clinical Research Center, Charite, Berlin

    collaborator OTHER

  • Charite University, Berlin, Germany

    lead OTHER

Principal Investigators

  • Andreas Meisel, Prof. Dr. · Charite University, Berlin, Germany

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-06-30
Primary Completion
2018-04-30
Completion
2018-04-30

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02008604 on ClinicalTrials.gov