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MUcociliary Clearance IN Stroke

NCT03884166 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 24

Last updated 2022-03-25

No results posted yet for this study

Summary

Stroke patients frequently suffer from stroke associated pneumonia. Pathophysiologically speaking, dysphagia and central nervous system (CNS)-injury induced immunosuppression largely contribute to the risk for pneumonia. In mouse models for stroke, the self-cleaning mechanisms of the lung are also affected by stroke, possibly further contributing to this risk.

The investigators designed a pilot-study to examine the structural and functional integrity of the self-cleaning mechanisms of the lung in stroke patients.

Conditions

  • Stroke, Ischemic

Interventions

DIAGNOSTIC_TEST

bronchoscopy

Patients will undergo bronchoscopy to sample respiratory tissue in different heights in order to analyze mucociliary clearance

Sponsors & Collaborators

  • NeuroCure Clinical Research Center, Charite, Berlin

    collaborator OTHER

  • Department of Infectiology and Pneumonology, Charite, Berlin

    collaborator UNKNOWN

  • University of Giessen

    collaborator OTHER

  • University of Luebeck

    collaborator OTHER

  • Labor Berlin - Charité Vivantes GmbH

    collaborator UNKNOWN

  • Charite University, Berlin, Germany

    lead OTHER

Principal Investigators

  • Andreas Meisel, Prof. Dr. med. · Charite University, Berlin, Germany

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-06-30
Primary Completion
2022-12-01
Completion
2022-12-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03884166 on ClinicalTrials.gov