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Determination of Adipocytokine in Synovial Fluid of Osteoarthritis Patients

NCT01993342 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 35

Last updated 2013-11-25

No results posted yet for this study

Summary

The purpose of this study is to determine the concentration of different adipocytokine (adiponectin, leptin, resistin, visfatin, osteopontin) and an inflammation classic markers as Interleukine 1 beta, tumor necrosis alfa, interleukine 6 and high sensibility reactive c protein in the synovial fluid of knee osteoarthritis patients, and compare with the inflammation detected with ultrasonography evaluation of the joint. In last years, some studies appeared focusing on the role of adipocytokines in osteoarthritis and they correlated adipocytokines with cartilage degradation and x-ray degree; in our study we will focused in the importance of adipocytokines in the inflammatory changes more than in joint destruction.

Conditions

Interventions

OTHER

arthrocentesis

The made a diagnostic arthrocentesis to all patient we included

OTHER

ultrasonography of the knee

We explored the affected knee with an ultrasound explanation in order to describe inflammatory changes based on standard examination.

Sponsors & Collaborators

  • Parc Taulí Hospital Universitari

    lead OTHER

Principal Investigators

  • Joan Calvet, Dr · Hospital Parc Tauli

  • Cristobal Orellana, Dr · Hospital Parc Tauli

Eligibility

Min Age
50 Years
Max Age
81 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-10-31
Primary Completion
2013-11-30
Completion
2014-03-31

Countries

  • Spain

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01993342 on ClinicalTrials.gov