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CAndesartan vs LIsinopril Effects on the BRain

NCT01984164 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 176

Last updated 2021-02-21

Study results available
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Summary

The aim of this study is to conduct a 1-year double blind randomized control trial comparing candesartan to lisinopril in 140 individuals with hypertension and executive mild cognitive impairment in their effects on executive function, neuroimaging markers, and vascular indicators.

Conditions

Interventions

DRUG

Candesartan

blinded

DRUG

Lisinopril

Blinded

Sponsors & Collaborators

  • National Institute on Aging (NIA)

    collaborator NIH

  • Emory University

    lead OTHER

Principal Investigators

  • Ihab Hajjar, MD, MS · Emory Univeristy

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-08-20
Primary Completion
2018-12-03
Completion
2018-12-03
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01984164 on ClinicalTrials.gov