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Experimental Exposure to Air Pollutants and Sympathetic Nerve Activity in Human Subjects

NCT01914783 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2013-08-02

No results posted yet for this study

Summary

The primary hypothesis of the study is that in healthy elderly subjects experimental exposure to air pollutants increases sympathetic nervous system activity compared with sham (clean air) exposure. The secondary hypothesis of the study is that combined experimental exposure to air pollutants (particles + ozone) increases sympathetic nervous system activity to a greater extent than does the exposure to particles alone.

Conditions

  • Cardiovascular Morbidity

Interventions

OTHER

ultrafine particles

exposure to ultrafine particles

OTHER

ultrafine particles and ozone

exposure to ultrafine particles and ozone

OTHER

clean air

Exposure to clean air.

Sponsors & Collaborators

  • Fraunhofer-Institute of Toxicology and Experimental Medicine

    collaborator OTHER

  • Hannover Medical School

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-07-31
Primary Completion
2015-12-31
Completion
2015-12-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01914783 on ClinicalTrials.gov