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Ventilation Strategy Reduces Postoperative Atelectasis

NCT01911923 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2014-08-26

No results posted yet for this study

Summary

Atelectasis is common during and after general anesthesia. The investigators hypothesized that a ventilation strategy with a combination of 1) continuous positive airway pressure (CPAP) or positive end-expiratory pressure (PEEP) and 2) a reduced end-expiratory oxygen fraction (FETO2) before commencing mask ventilation with CPAP after extubation would reduce the area of postoperative atelectasis.

Conditions

  • Pulmonary Atelectasis

Interventions

PROCEDURE

No CPAP/PEEP and 100 % oxygen

This is the control group and 100 % oxygen will be used during induction of and emergence from anesthesia, no enhanced level of CPAP/PEEP is implemented. During controlled ventilation ventilation mode is volume controlled.

PROCEDURE

CPAP/PEEP and 30 % oxygen

During all phases of anesthesia CPAP/PEEP will be used together with 100 % oxygen during induction of as well during emergence from anesthesia until after extubation when 30 % oxygen will be used.

Sponsors & Collaborators

  • Region Västmanland

    lead OTHER

Principal Investigators

  • Lennart Edmark, Md · Landstinget Vastmaland

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-08-31
Primary Completion
2013-11-30
Completion
2013-11-30

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01911923 on ClinicalTrials.gov