Muscle Metabolism and Oxygenation During Localized Fatigue-exercise in COPD
NCT01909544 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2014-02-07
Summary
The purpose of this study is to investigate whether a localized exercise, in which cardiorespiratory demand is reduced, will result in greater limb muscle fatigue in patients with COPD as a consequence of muscle oxygenation and muscle metabolism disturbances.
Conditions
- Pulmonary Disease, Chronic Obstructive
Interventions
- OTHER
-
Fatiguing exercise
All participants (patients and healthy subjects) will perform the exercise both under normoxic (FiO2 = 0.21) and hyperoxic conditions (FiO2 = 100%)
Sponsors & Collaborators
-
Canadian Lung Association
collaborator INDUSTRY -
Laval University
lead OTHER
Principal Investigators
-
François Maltais, MD · Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 50 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2011-09-30
- Primary Completion
- 2014-07-31
Countries
- Canada
Study Locations
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