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Effect of Non Invasive Brain Stimulation on Experimentally Induced Dyspnea (Breathlessness)

NCT01892553 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2014-05-06

No results posted yet for this study

Summary

Dyspnea is a frequent, mostly unpleasant and long-lasting, but also often undertreated symptom. Transcranial direct current stimulation (tDCS), a new non invasive method to modify brain activation has shown good efficacy in the treatment of pain especially in the clinical context. Given the fact that dyspnea has many common characteristics with pain, especially concerning the brain areas involved in its central processing, we hypothesize that tDCS may also modify the perception of dyspnea. In order to test this, we first shall determine whether tDCS has a significant effect on acutely induced dyspnea in healthy volunteers. In case of promising results of this pilot study, the next step will be the evaluation of the benefit of tDCS in patients with severe dyspnea.

Conditions

Interventions

DEVICE

tDCS

Procedure : 3 different sessions of tDCS (listed below) presented in random order, each applied at a different study visit * Anodal tDCS: Intensity of 1.25 milliAmperes (mA) during 15 min * Cathodal tDCS: Intensity of 1.25 mA during 15 min * Sham tDCS (placebo) (1.25 mA maintained only during the first 30 sec of the 15 minutes application)

Sponsors & Collaborators

  • Adep Assistance

    collaborator OTHER

  • Centre d'Investigation Clinique et Technologique 805

    lead OTHER

Principal Investigators

  • CLAUDINE PEIFFER, MD PHD · HOPITAL RAYMOND POINCARE

Study Design

Allocation
RANDOMIZED
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-07-31
Primary Completion
2014-03-31
Completion
2014-04-30

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01892553 on ClinicalTrials.gov