The FDA approved Tecvayli plus Darzalex Faspro for relapsed/refractory multiple myeloma in March 2026, and Darzalex Faspro-based quadruplet D-VRd for newly diagnosed transplant-ineligible patients in January 2026.
The FDA has approved Filkri (filgrastim-laha), a biosimilar to Neupogen, for cancer patients at risk of infection due to chemotherapy and other indications. The approval marks Accord BioPharma's sixth biosimilar product.
The FDA approved multiple denosumab biosimilars in late 2025 and issued REMS safety updates emphasizing severe hypocalcemia risk in patients with advanced chronic kidney disease, including reported hospitalizations and fatalities.
The FDA approved a once-monthly dosing schedule for Rybrevant Faspro with Lazcluze for first-line treatment of EGFR-mutated advanced NSCLC, reducing clinic visits while maintaining safety and efficacy established with bi-weekly dosing.
The FDA approved Zycubo (copper histidinate) on January 13, 2026, as the first treatment for Menkes disease in pediatric patients, following resolution of manufacturing compliance concerns that led to an initial rejection in September 2025.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07591987 |
Effect of Different Breathing Techniques on Dyspnea and Cardiopulmonary Parameters Among Patients After Open Heart Surgery |
RECRUITING | NA |
| NCT07542691 |
Respiratory Physiotherapy and PMR After Cardiac Surgery |
NOT_YET_RECRUITING | NA |
| NCT07497230 |
Asymmetric High-Flow Nasal Cannula During Pulmonary Rehabilitation in COPD |
COMPLETED | NA |
| NCT07386444 |
Inspiratory Muscle Training for Breast Cancer Patients on Chemotherapy |
RECRUITING | NA |
| NCT07324980 |
Acute DYSPnea in the Emergency Department: Diagnostic Value of Point-of-care UltraSound |
RECRUITING | |
| NCT07268859 |
Effect of Fan Application in Preventing Ticagrelor-Associated Dyspnea |
RECRUITING | NA |
| NCT07257705 |
Pilot Trial of a Clinical Decision-Support App for Managing Emergencies Among Clinicians in a Rural Ugandan Hospital |
COMPLETED | NA |
| NCT07228676 |
INSPIRatory Efforts Estimation Under High-flow Nasal Oxygen |
COMPLETED | NA |
| NCT07184372 |
Radiofrequency in Patients Post Covid 19 With Respiratory Sequelae. |
COMPLETED | NA |
| NCT07182695 |
Cervical Erector Spinae Plane Block for Dyspnea in Acute Respiratory Failure: A Prospective Cohort |
NOT_YET_RECRUITING |
