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Efficacy of Antioxidant Therapy Compared With Enalapril in Sickle Nephropathy

NCT01891292 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2013-07-03

No results posted yet for this study

Summary

The purpose of this study is to determine whether enalapril or antioxidant therapy (N-Acetylcysteine) is effective in reducing microalbuminuria in children with sickle cell disease and and its progression to sickle nephropathy

Conditions

  • Microalbuminuria
  • Sickle Cell Nephropathy

Interventions

DRUG

Enalapril

0.25-0.35 mg/kg/day

DRUG

N-Acetylcysteine

N-Acetylcysteine 0.5 mmol/kg

Sponsors & Collaborators

  • Caribbean Health Research Council

    collaborator OTHER

  • The University of The West Indies

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
2 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-07-31
Primary Completion
2014-08-31
Completion
2015-09-30

Countries

  • Jamaica

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01891292 on ClinicalTrials.gov