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Risk of Uncomplicated Peptic Ulcer in the General Population

NCT01888588 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 4000

Last updated 2014-07-15

No results posted yet for this study

Summary

The analyses are conducted in a previous population-based cohort study using The Health Improvement Network database in the UK (Cai et al 2009).The aims of the post hoc analyses are:

To estimate the relative risk of uncomplicated symptomatic peptic ulcer (UPU) associated with use of low dose aspirin (ASA) and other anti-inflammatory drugs (NSAIDs, steroids) in the general population To estimate the dose-response and duration-response associated with use of these drugs To estimate the relative risk of UPU associated with naive/non-naive use of low dose ASA in the general population To evaluate the effect of proton pump inhibitors (PPI) (alone or in combination with anti-inflammatory drugs) on the occurrence of UPU in the general population To investigate the management of low dose ASA/oral antiplatelets after UPU

Conditions

  • Peptic Ulcer [Iowa Type (107680.0010)]

Interventions

DRUG

Risk of symptomatic peptic ulcer

Current use of drugs (ASA; NSAIDs, SSRI,PPI, H2RA) versus non-use

Sponsors & Collaborators

Principal Investigators

  • Luis A Garcia Rodriguez, MD · CEIFE (Centro Espanol de Investigacion Farmacoepidemiologica - Spanish Centre for Pharmacoepidemiologic Research )

Eligibility

Min Age
40 Years
Max Age
84 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-09-30
Primary Completion
2013-05-31
Completion
2013-05-31

Countries

  • Spain

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01888588 on ClinicalTrials.gov