The Study on Profile and Genetic Factors of Aspirin Resistance (ProGEAR Study)

Summary

The purpose of this study is to determine the clinically meaningful definition and prevalence of aspirin resistance based on data linking aspirin-dependent laboratory tests to recurrent vascular events in cardiovascular patients taking aspirin.

Conditions

• Coronary Disease
• Cerebral Infarction
• Ischemic Attack, Transient

Sponsors & Collaborators

• The National Institute of Biomedical Innovation

  collaborator UNKNOWN

• Ministry of Health, Labour and Welfare, Japan

  lead OTHER_GOV

Principal Investigators

• Toshiyuki Miyata, PhD · National Cardiovascular Center, Research Institute,

• Shigeki Miyata, MD · National Cerebral and Cardiovascular Center, Japan

• Kazuo Minematsu, MD · National Cerebral and Cardiovascular Center, Japan

• Masafumi Kitakaze, MD, PhD · National Cerebral and Cardiovascular Center, Japan

• Kazuyuki Nagatsuka, MD, PhD · National Cerebral and Cardiovascular Center, Japan

• Atsushi Kawamura, MD, PhD · National Cerebral and Cardiovascular Center, Japan

• Akiko Kada, MPH · National Cerebral and Cardiovascular Center, Japan

• Shinichiro Uchiyama, MD · Tokyo Women's Medical University

• Takehiko Nagao, MD, PhD · Tokyo Metropolitan Ebara Hospital

• Naohisa Hosomi, MD, PhD · Kagawa University School of Medicine

• Takemori Yamawaki, MD, PhD · Nagoya City University Graduate School of Medical Science

• Kazumi Kimura, MD, PhD · Kawasaki Medical School

• Kozue Saito, MD · Nara Medical University

• Hiroshi Nakane, MD · National Fukuoka-Higashi Medical Center

• Jyoji Nakagawara, MD · Nakamura Memorial Hospital

• Shinya Goto, MD · Tokai University School of Medicine

• Takaaki Isshiki, MD · Teikyo University

• Kazuo Kitagawa, MD · Osaka University Graduate School of Medicine

• Kazuomi Kario, MD · Jichi Medical School

• Hideo Wada, MD, PhD · Mie University Graduate School of Medicine

• Ken Nagata, MD · Research Institute for Brain and Blood Vessels Akita

• Koichi Kaikita, MD · Kumamoto University Graduate School of Medicine

• Keiji Tanaka, MD · Nippon Medical School Hospital

• Akira Hattori, MD · Sado Hospital

• Eisuke Furui, MD, PhD · Kohnan Hospital

• Yoshihiko Saito, MD, PhD · Nara Medical University

• Satoshi Ueno, MD · Nara Medical University

• Yasuo Katayama, MD · Nippon Medical School Hospital

• Takeo Abumiya, MD · Hokkaido Neurosurgical Memorial Hospital

• Masakatsu Nishikawa, MD · Mie University Graduate School of Medicine

• Shin Takiuchi, MD, PhD · Higashi Takarazuka Satoh Hospital

• Hideyuki Ohnishi, MD · Ohnishi Neurological Center

Eligibility

Min Age

20 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2005-11-30

Primary Completion

2010-06-30

Completion

2011-03-31

Countries

• Japan

Study Locations