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Phenylketonuria and Hyperphenylalaninemia Nutrition Study

NCT01879995 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2016-02-08

No results posted yet for this study

Summary

The mainstay of PKU treatment is a low-phenylalanine diet (i.e restriction of natural protein), and supplementation with a protein substitute (a mixture of amino acids free from phenylalanine, also containing micronutrients and vitamins) and special low-protein foods, to meet the patient's energy requirements. When diet and treatment is relaxed after childhood, adult and adolescent patients with phenylketonuria are at risk for malnutrition, depending on the compliance with treatment and the intake of amino acid supplements.

In this study, nutrition status of patients with PKU and hyperphenylalaninemia is systematically assessed under ongoing current treatment, in relation to Phe-tolerance, compliance with treatment, and psychosocial issues.

Study participants do not undergo any specific therapeutic or diagnostic intervention.

Conditions

  • Phenylketonuria (PKU) and Hyperphenylalaninemia

Interventions

PROCEDURE

Sponsors & Collaborators

  • University of Zurich

    lead OTHER

Principal Investigators

  • Michel Hochuli, MD PhD · University Hospital Zurich, Division of Endocrinology, Diabetes and Clinical Nutrition

Eligibility

Min Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-06-30
Primary Completion
2015-07-31
Completion
2015-07-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01879995 on ClinicalTrials.gov