The Bacteriuria in Renal Transplantation (BiRT) Study: A Trial Comparing Antibiotics Versus no Treatment in the Prevention of Symptomatic Urinary Tract Infection in Kidney Transplant Recipients With Asymptomatic Bacteriuria

Summary

The purpose of this study is to compare antibiotics versus no-treatment in kidney transplant recipients with asymptomatic bacteriuria.

Conditions

• Asymptomatic Bacteriuria
• Bacteriuria
• Urinary Tract Infections
• Kidney Transplantation

Interventions

OTHER

Anti-Infective Agents

10 days of antibiotics, started and selected according to the antibiogram results. In case of reinfection or relapse, re-administration of antimicrobial agents will be performed according to the antibiogram results (for a maximum of 3 cycles of ten days of antibiotics during the 12 months of the follow-up)

Sponsors & Collaborators

• University Hospital, Lille

  collaborator OTHER

• Universitair Ziekenhuis Brussel

  collaborator OTHER

• Hôpital Necker Enfants-Malades, Université de Paris Descartes, APHP, France

  collaborator UNKNOWN

• Centre Hospitalier Universitaire Brugmann

  collaborator OTHER

• Centre Hospitalier Universitaire de Charleroi

  collaborator OTHER

• University Ghent

  collaborator OTHER

• Centre Hospitalier Epicura, Belgium

  collaborator UNKNOWN

• University of Liege

  collaborator OTHER

• Nantes University Hospital

  collaborator OTHER

• Erasme University Hospital

  lead OTHER

Principal Investigators

• Julien Coussement, MD · Hôpital Universitaire Erasme, Brussels, Belgium

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-04-30

Primary Completion

2019-07-31

Completion

2019-07-31

Countries

• Belgium
• France

Study Locations