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Polish Mother and Child Cohort Study (REPRO_PL) - Follow up of the Children.

NCT01861548 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 479

Last updated 2013-05-23

No results posted yet for this study

Summary

The Polish Mother and Child Cohort is multicentre prospective study on different exposures.

Prospective cohort study design enables identification of exposures that may influence pregnancy outcome and chil-dren's health, verification of such exposures by biomarker measurements and notification of any changes in exposure levels.

The aim of the study is to evaluate the impact of exposure to different environmental factors during pregnancy and after birth on pregnancy outcome and children's health. Specific research hypotheses refer to the role of heavy metals, exposure to polycyclic aromatic hydrocar-bons (PAHs) and environmental tobacco smoke (ETS) in the aetiology of intrauterine growth retardation (IUGR), preterm delivery (PD) and the risk of respiratory diseases, allergy and poor mental and physical development. It is also intended to explain the role of oxidative stress and nutritional status of the pregnant women. The impact of occupational exposures and stressful situations on pregnancy outcome will be evaluated from question-naire data.

The results of the study will help to determine levels of child prenatal and postnatal exposure in several areas of Poland and their im-pact on course and outcome of pregnancy and children's health.

This protocol concerns the children that are followed-up from birth to the age of 2 years to determine long term effects of pre- and postnatal environmental exposures.

Conditions

Sponsors & Collaborators

  • Medical University of Lodz

    lead OTHER

Principal Investigators

  • Iwona Stelmach, MD,PhD,Prof. · Department of Pediatrics and Allergy, Medical University of Lodz, N. Copernicus Hospital, Lodz, Poland

  • Monika Kopka, MD · Department of Pediatrics and Allergy, Medical University of Lodz, N. Copernicus Hospital, Lodz, Poland

  • Wojciech Hanke, MD,PhD,Prof. · Nofer Institute of Occupational Medicine, Department of Environmental Epidemiology

  • Kinga Polanska, MD, PhD · Nofer Institute of Occupational Medicine, Department of Environmental Epidemiology

Eligibility

Min Age
1 Minute
Max Age
24 Months
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-01-31
Primary Completion
2013-05-31
Completion
2013-05-31

Countries

  • Poland

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01861548 on ClinicalTrials.gov