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Immune Response Features in Allergic Airway Diseases

NCT04352088 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 150

Last updated 2020-04-17

No results posted yet for this study

Summary

This study aims to investigate immune mechanisms and phenotypes and endotypes of allergic airway diseases - allergic rhinitis and allergic asthma. Pathogenesis of these diseases are not fully investigated yet. Patients with the same disease have different dominant symptoms, course of the disease and response to treatment. Moreover, there is a hypothesis about united airway disease suggesting that allergic rhinitis and allergic asthma is different manifestation of the same disease. This led to assumption of phenotypes and endotypes. This classification which still is not unified can let to prescribe personalized treatment for every patient.

Conditions

  • Allergic Rhinitis
  • Allergic Asthma

Interventions

PROCEDURE

Nasal provocation test

Allergen extract under controlled conditions will be applied into nasal mucous.

Sponsors & Collaborators

  • Lithuanian University of Health Sciences

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-05-01
Primary Completion
2022-11-30
Completion
2024-04-30

Countries

  • Lithuania

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04352088 on ClinicalTrials.gov