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CRAGS (Coronary aRtery diseAse in younG adultS)

NCT01838746 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 2000

Last updated 2015-05-28

No results posted yet for this study

Summary

Young patients requiring myocardial revascularization are generally considered at low operative risk, but data on their immediate and late outcome are scarce. The decision-making process in these young patients is complicated by the potentially aggressive nature of premature coronary artery disease and their likely long expectancy of life, which expose them to a significantly higher risk of recurrent coronary events as well as the need of repeat revascularization. The lack of data on long-term outcome as well as on operative details (in particular, on the use of arterial grafts) and peri- and postoperative medication prevent any conclusive results on the durability either of coronary artery bypass grafting (CABG) or of percutaneous coronary intervention (PCI) in these young patients. Furthermore, recent advances in stents technology as well in peri- and postoperative medical treatment indicate the need a comparative study to define the baseline characteristics of patients aged \< 50 years undergoing either PCI or CABG and to evaluate their current immediate and late outcome.

Conditions

  • Coronary Artery Disease
  • Acute Coronary Syndromes
  • Young Patient
  • Percutaneous Coronary Intervention
  • Coronary Artery Bypass Grafting

Sponsors & Collaborators

  • Finnish Foundation for Cardiovascular Research

    collaborator OTHER

  • University of Turku

    lead OTHER

Principal Investigators

  • Fausto Biancari, MD, PhD · Oulu University Hospital

  • Juhani Airaksinen, MD, PhD · Turku University Hospital

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-04-30
Primary Completion
2014-12-31
Completion
2016-12-31

Countries

  • Finland
  • Iceland
  • Italy
  • Sweden

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01838746 on ClinicalTrials.gov