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Brain Perfusion in Pantothenate Kinase-associated Neurodegeneration (PKAN)

NCT01838018 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 10

Last updated 2018-05-29

No results posted yet for this study

Summary

The purpose of this study is to learn whether blood flow in the brain is normal in people with pantothenate kinase-associated neurodegeneration (PKAN). Specifically, preliminary data suggest a region of the brain called the globus pallidus (GP), a key region affected by PKAN, may have reduced blood flow. Standard MRI and perfusion scanning techniques will be used to learn about cerebral blood flow in the globus pallidus and compare it to blood flow in other brain regions as well as to healthy controls.

Conditions

  • Pantothenate Kinase-associated Neurodegeneration (PKAN)

Sponsors & Collaborators

  • Oregon Health and Science University

    collaborator OTHER

  • Oregon Clinical and Translational Research Institute

    collaborator OTHER

  • Susan J. Hayflick

    lead OTHER

Principal Investigators

  • Susan J Hayflick, MD · Oregon Health and Science University

Eligibility

Min Age
7 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-04-30
Primary Completion
2017-10-31
Completion
2018-01-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01838018 on ClinicalTrials.gov