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Methadone for Postoperative Pain

NCT01833715 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 86

Last updated 2023-09-26

No results posted yet for this study

Summary

The aim of this study is to compare the efficacy of methadone versus morphine in dealing with postoperative pain, in laparoscopic cholecystectomy under total intravenous anesthesia (TIVA); Efficacy is defined in terms of the difference of milligrams in morphine used as rescue analgesia postoperatively. Our hypothesis is that methadone is more effective than morphine for postoperative pain treatment.

Conditions

  • Pain, Postoperative

Interventions

DRUG

Morphine

Morphine group,receive morphine 0.08 mg / kg at the start of surgery

DRUG

Methadone

Methadone group,receive methadone 0.08 mg / kg at the start of surgery

DRUG

TIVA

TIVA: General anesthesia will be based on Remifentanil and Propofol (TIVA-TCI), titrated to achieve bispectral index (BIS) between 40 and 60.

Sponsors & Collaborators

  • Universidad de Valparaiso

    lead OTHER

Principal Investigators

  • NICOLAS ARRIAZA, Physician · University Valparaiso

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-03-31
Primary Completion
2013-08-31
Completion
2013-09-30

Countries

  • Chile

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01833715 on ClinicalTrials.gov