Autologous Dendritic Cells in Treating Patients With Metastatic Kidney Cancer
NCT01826877 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2021-08-04
Summary
This phase I trial studies the side effects and best dose of autologous dendritic cells in treating patients with metastatic kidney cancer. Vaccines made from a person's tumor cells and white blood cells may help the body build an effective immune response to kill tumor cells.
Conditions
- Clear Cell Renal Cell Carcinoma
- Recurrent Renal Cell Cancer
- Stage IV Renal Cell Cancer
Interventions
- BIOLOGICAL
-
AdGMCAIX-transduced autologous dendritic cells
Given ID
- BIOLOGICAL
-
therapeutic autologous dendritic cells
Given ID
- OTHER
-
laboratory biomarker analysis
Correlative studies
Sponsors & Collaborators
-
Kite, A Gilead Company
collaborator INDUSTRY -
Jonsson Comprehensive Cancer Center
lead OTHER
Principal Investigators
-
Alexandra Drakaki, MD · Jonsson Comprehensive Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-01-14
- Primary Completion
- 2018-07-03
- Completion
- 2021-05-27
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Vaccine Therapy in Treating Patients With Kidney Cancer
NCT00014131 ·Status: TERMINATED ·Phase: PHASE1
-
DC Vaccine Therapy Combined With Cytokine-Induced Killer Cell in Treating Patients With Renal Cell Carcinoma
NCT00862303 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Dendritic Killer Cell-based Immunotherapy for Solid Tumors
NCT02882659 ·Status: UNKNOWN ·Phase: PHASE1
-
Study Testing the Biologic Activity and Safety of an Immunotherapeutic in Patients With Newly Diagnosed Stage IV Kidney Cancer
NCT00272649 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
DC Vaccine Therapy Combined With Cytokine-Induced Killer Cell in Treating
NCT02487550 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Autologous Dendritic Cell Vaccine in Kidney Cancer
NCT05127824 ·Status: RECRUITING ·Phase: PHASE2
-
Vaccination of Patients With Renal Cell Cancer With Dendritic Cell Tumor Fusions and GM-CSF
NCT00458536 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Clinical Study to Evaluate Safety and Immunologic Response of COMBIG-DC, in Patients With Metastatic Kidney Cancer
NCT01525017 ·Status: COMPLETED ·Phase: PHASE1
-
DC Vaccine Combined With IL-2 and IFNα-2a in Treating Patients With mRCC
NCT00085436 ·Status: COMPLETED ·Phase: PHASE2
-
Dendritic Cell Vaccine for Head and Neck Cancer
NCT00492947 ·Status: WITHDRAWN ·Phase: PHASE1
-
Engineered Dendritic Cell Vaccines for Multiple Myeloma
NCT06435910 ·Status: RECRUITING ·Phase: PHASE1
-
Specialized Immune Cells (nCTLs) and a Vaccine (Alpha-type-1 Polarized Dendritic Cells) in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
NCT03735589 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
DC Vaccine Combined With CIK Cells in Patients With Renal Cell Carcinoma
NCT01924156 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Immune Responses to Autologous Langerhans-type Dendritic Cells Electroporated With mRNA Encoding a Tumor-associated Antigen in Patients With Malignancy: A Single-arm Phase I Trial in Melanoma
NCT01456104 ·Status: COMPLETED ·Phase: PHASE1
-
Dendritic Cell Vaccination With Standard Postoperative Chemoradiation for the Treatment of Adult Glioblastoma
NCT04552886 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy in Treating Patients With Kidney Cancer
NCT00096629 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy in Treating Patients With Metastatic Prostate Cancer
NCT00010127 ·Status: TERMINATED ·Phase: PHASE1
-
Vaccine Therapy for Multiple Myeloma Utilizing Idiotype-Pulsed Allogeneic Dendritic Cells
NCT00186316 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Autologous Dendritic Cell-Tumor Cell Immunotherapy for Metastatic Melanoma
NCT01875653 ·Status: TERMINATED ·Phase: PHASE3
-
Dendritic Cells(DC)-Based Id Vaccination in Stage-I Myeloma
NCT00988312 ·Status: COMPLETED ·Phase: PHASE1
-
Vaccine Therapy in Treating Patients With Refractory Stage IV Cancer
NCT00057915 ·Status: COMPLETED ·Phase: PHASE1
-
Active Immunotherapy Of Metastatic Renal Cell Carcinoma Using Autologous Dendritic Cells Transfected With Autologous Total Tumor RNA
NCT00006431 ·Status: UNKNOWN ·Phase: PHASE1
-
Donor Natural Killer Cells After Donor Stem Cell Transplant in Treating Patients With Advanced Cancer
NCT00823524 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Phase 1/2 Study of Metastatic Renal Cancer Using T-Cells Transduced With a T-Cell Receptor Which Recognizes TRAIL Bound to the DR4 Receptor
NCT00923390 ·Status: TERMINATED ·Phase: PHASE1
-
Safety Study of Adoptive Transfer of Autologous IKDC-like Cells
NCT02661685 ·Status: COMPLETED ·Phase: PHASE1