Study Testing the Biologic Activity and Safety of an Immunotherapeutic in Patients With Newly Diagnosed Stage IV Kidney Cancer
NCT00272649 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 22
Last updated 2013-03-14
Summary
The purpose of this trial is to examine the safety, feasibility, immunological response, and clinical antitumor activity of multiple administrations of dendritic cell Immunotherapeutic to patients with newly diagnosed with metastatic kidney cancer
Conditions
Interventions
- BIOLOGICAL
-
AGS-003
Dendritic cell, autologous cellular immunotherapy. (Arcelis platform)
Sponsors & Collaborators
-
Argos Therapeutics
lead INDUSTRY
Principal Investigators
-
Terry Chew, MD · Argos Therapeutics
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-01-31
- Primary Completion
- 2012-02-29
- Completion
- 2012-02-29
Countries
- United States
- Canada
Study Locations
More Related Trials
-
Dendritic Cell Vaccination in Melanoma Patients Scheduled for Regional Lymph Node Dissection
NCT00243594 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Vaccine Therapy in Treating Patients With Kidney Cancer
NCT00014131 ·Status: TERMINATED ·Phase: PHASE1
-
Vaccine Therapy in Treating Patients With Refractory Stage IV Cancer
NCT00057915 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1/2 Study of Metastatic Renal Cancer Using T-Cells Transduced With a T-Cell Receptor Which Recognizes TRAIL Bound to the DR4 Receptor
NCT00923390 ·Status: TERMINATED ·Phase: PHASE1
-
A Phase 1 Study of MEDI0562 in Adult Subjects With Selected Advanced Solid Tumors
NCT02318394 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I/II Study to Assess the Safety and Efficacy of Vaccinations With Allogeneic Dendritic Cells: Autologous Tumor-Derived Cells Subjected to Electrofusions in Patients With AJCC Stage IV Renal Cell Carcinoma
NCT00625755 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Safety/Efficacy of a Vaccine Prepared From Dendritic Cells Combined With Tumor Cells to Treat Advanced Kidney Cancer
NCT00050323 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Single-step Antigen Loading and TLR Activation of Dendritic Cells in Melanoma Patients
NCT01530698 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study in Adult Subjects With Select Advanced Solid Tumors
NCT02583165 ·Status: COMPLETED ·Phase: PHASE1
-
MIDRIXNEO-LUNG Dendritic Cell Vaccine in Patients With Non-small Cell Lung Cancer
NCT04078269 ·Status: COMPLETED ·Phase: PHASE1
-
Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer
NCT05620342 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Immune Responses to Autologous Langerhans-type Dendritic Cells Electroporated With mRNA Encoding a Tumor-associated Antigen in Patients With Malignancy: A Single-arm Phase I Trial in Melanoma
NCT01456104 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I, 2-part (Part 1 Being a Single Dose Escalation and Part 2, a Parallel Group) Study of Toll-like Receptor (TLR4) Agonist (GSK1795091) in Healthy Subjects
NCT02798978 ·Status: COMPLETED ·Phase: PHASE1
-
Dendritic Cell Vaccination for Patients with Solid Tumors
NCT01291420 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Reconstitution of a Human Immune System in a Patient Derived Xenograft (PDX) Model of Genitourinary (GU) Cancers
NCT03134027 ·Status: TERMINATED
-
Exploring Relevant Immune-based Biomarkers and Circulating Tumor Cells During Treatment With Immunotherapy in Genitourinary Malignancies (CTC Immune Based Biomarkers)
NCT02978118 ·Status: ACTIVE_NOT_RECRUITING
-
Vaccine Therapy in Treating Patients With Stage I, Stage II, or Stage III Non-small Cell Lung Cancer
NCT00103116 ·Status: COMPLETED ·Phase: PHASE2
-
Complementary Vaccination With Dendritic Cells Pulsed With Autologous Tumor Lysate in Resected Stage III and IV Melanoma Patients.
NCT02718391 ·Status: TERMINATED ·Phase: PHASE2
-
Autologous Dendritic Cell Vaccine in Kidney Cancer
NCT05127824 ·Status: RECRUITING ·Phase: PHASE2
-
Peptide-pulsed vs. RNA-transfected Dendritic Cell Vaccines in Melanoma Patients
NCT00243529 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Investigation of Lymph Node Biology in Kidney Cancer
NCT07038733 ·Status: RECRUITING ·Phase: NA
-
Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Express TCRs
NCT05292859 ·Status: COMPLETED
-
Melanoma Patients Immunized with Natural DenDritic Cells
NCT02993315 ·Status: COMPLETED ·Phase: PHASE3
-
Clinical Safety and Preliminary Efficacy of AAV-DC-CTL Treatment in Stage IV Gastric Cancer
NCT01637805 ·Status: UNKNOWN ·Phase: PHASE1
-
NKG2D CAR-T(KD-025) in the Treatment of Advanced NKG2DL+ Solid Tumors
NCT06509490 ·Status: RECRUITING ·Phase: NA