MedTrace Logo

18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing Sarcoma

NCT01825902 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 1

Last updated 2017-11-20

No results posted yet for this study

Summary

This pilot trial studies fluorine F 18 fluorothymidine (18F-FLT) positron emission tomography and diffusion-weighted magnetic resonance imaging in planing surgery and radiation therapy and measuring response in patients with newly diagnosed Ewing sarcoma. Comparing results of diagnostic procedures done before and after treatment may help doctors predict a patient's response and help plan the best treatment.

Conditions

  • Adult Supratentorial Primitive Neuroectodermal Tumor (PNET)
  • Ewing Sarcoma of Bone
  • Extraosseous Ewing Sarcoma
  • Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
  • Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
  • Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor

Interventions

DRUG

fluorine F 18 fluorothymidine

Undergo 18F-FLT PET

RADIATION

fludeoxyglucose F 18

Undergo 18F-FDG PET

PROCEDURE

positron emission tomography

Undergo 18F-FLT PET and 18F-FDG PET

PROCEDURE

diffusion-weighted magnetic resonance imaging

Undergo DW-MRI

OTHER

laboratory biomarker analysis

Correlative studies

Sponsors & Collaborators

Principal Investigators

  • Nadia N. Laack, M.D. · Mayo Clinic

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
7 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-03-31
Primary Completion
2014-01-31
Completion
2015-11-23

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01825902 on ClinicalTrials.gov