3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer

NCT00935090 · Status: RECRUITING · Type: INTERVENTIONAL

Last updated 2025-07-08

No results posted yet for this study

Summary

RATIONALE: Diagnostic procedures, such as 3'-deoxy-3'-\[18F\] fluorothymidine (FLT) PET imaging, may help find and diagnose cancer. It may also help doctors predict a patient's response to treatment and help plan the best treatment.

PURPOSE: This phase I trial is studying FLT PET imaging in patients with cancer.

Conditions

Interventions

DEVICE

3'-deoxy-3'-[18F]fluorothymidine

The tracer compound \[F-18\] FLT will be injected into the patient's veins in a small volume of normal saline solution. The PET scan data collection is started immediately and is continued for 2 hours. This procedure will measure tumor growth within the body. Blood may be withdrawn (through the catheters) up to a total volume of 30 milliliters (or 2 tablespoons) for each scan. A urine sample may be collected at the end of the imaging of the tracer compound to analyze its breakdown products.

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH
  • Barbara Ann Karmanos Cancer Institute

    lead OTHER

Principal Investigators

  • Anthony F. Shields, MD, PhD · Barbara Ann Karmanos Cancer Institute

Eligibility

Min Age
18 Years
Max Age
120 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-09-30
Primary Completion
2027-05-31
Completion
2028-05-31

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00935090 on ClinicalTrials.gov