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Cough-Generated Aerosols of NTM in Cystic Fibrosis

NCT01815866 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 5

Last updated 2015-10-14

No results posted yet for this study

Summary

Non-tuberculous mycobacteria (NTM) are opportunistic pathogens normally found in soil and water that are being cultured from Cystic Fibrosis (CF) airways at an increasing frequency. They have been demonstrated to cause clinically significant lung disease in some cases and the transmission of NTM, from person to person has been proposed. There are currently no standardized guidelines for isolation of those colonized or infected with NTM.

The investigators will measure particle droplet size from patients with CF who have positive sputum cultures for NTM with the hypothesis that they will be in a range that can spread infection.

Conditions

Interventions

PROCEDURE

CF with culturable NTM

CF patients who produce culturable aerosols of NTM will receive the following test: pulmonary function test, collecting a sputum culture if possible, coughing for 5 minutes into a tube connected to a canister, hypertonic saline and albuterol will be given after the 5 minutes of coughing and then they would repeat with another 5 minutes of coughing. There can be a break inbetween the coughing if needed.

Sponsors & Collaborators

  • Children's Miracle Network

    collaborator OTHER

  • UF Peds

    collaborator UNKNOWN

  • University of Florida

    lead OTHER

Principal Investigators

  • Pamela M Schuler, MD · University of Florida

Eligibility

Min Age
8 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-04-30
Primary Completion
2015-07-31
Completion
2015-07-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01815866 on ClinicalTrials.gov