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Effect of Gastric Bypass Surgery on Brain Responses

NCT01815216 · Status: SUSPENDED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2015-06-02

No results posted yet for this study

Summary

After obesity surgery gastric bypass (GBP) patients usually lose more than 50% of its former preponderance in relative short time (\~ 2 years). But knowledge of the underlying biological mechanisms of decline in body weight is still inadequate.

This project intends to examine patients' background activity in the brain (i.e. "the resting state activity") and brain volume using MRI both before and one year after surgery.

Conditions

  • Obesity
  • Hormone Responses
  • Cognitive Health

Interventions

PROCEDURE

Bariatric surgery

Gastric bypass surgery

BEHAVIORAL

Brain activity in resting state

Measure of activity in brain networks during resting state

BEHAVIORAL

Memory performance

Assess concentration in 2D-location task (i.e. "memory game")

Sponsors & Collaborators

  • Uppsala University Hospital

    collaborator OTHER

  • Uppsala University

    lead OTHER

Principal Investigators

  • Magnus Sundbom, MD · Academic Hospital Uppsala

  • Christian Benedict, PhD · Uppsala University

  • Pleunie Hogenkamp, PhD · Uppsala University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-03-31
Primary Completion
2016-12-31
Completion
2016-12-31

Countries

  • Sweden

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01815216 on ClinicalTrials.gov