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Supplemental Perioperative Oxygen to Reduce Surgical Site Infection After High Energy Fracture Surgery

NCT01798810 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1171

Last updated 2026-05-05

No results posted yet for this study

Summary

The OXYGEN Study is a double blinded prospective randomized controlled trial that will compare the proportion of surgical site infections within 6 months in patients treated with Supplemental Perioperative Oxygen compared to those treated without Supplemental Perioperative Oxygen.

Conditions

  • Post Operative Surgical Site Infection

Interventions

PROCEDURE

Supplemental Perioperative Oxygen

Patients receiving perioperative oxygen will receive 80% FiO2 during surgery.

Sponsors & Collaborators

  • Major Extremity Trauma Research Consortium

    lead OTHER

Principal Investigators

  • Renan Castillo, PhD · Johns Hopkins Bloomberg School of Public Health

  • Robert O'Toole, MD · University of Maryland R Adams Cowley Shock Trauma Center

  • Anthony Carlini, MS · Johns Hopkins Bloomberg School of Public Health

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-06-30
Primary Completion
2019-05-31
Completion
2022-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01798810 on ClinicalTrials.gov