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Vitamin D Retrospective Study and Role With Disease

NCT01798030 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 362

Last updated 2021-07-20

No results posted yet for this study

Summary

Vitamin D deficiency is associated with a heightened risk for developing type 2 diabetes, hypertension, and osteopenia/osteoporosis. Vitamin D is made in the skin when it is exposed to sunlight and it is also obtained from the diet and dietary supplements. Older people, individuals with high skin pigmentation, obese and sedentary individuals have low levels of Vitamin D because pigmentation blocks Vitamin D production in the skin, aging and physical inactivity are associated with reduced exposure to sunlight, and obesity is associated with the storage of Vitamin D in fat preventing its utilization by muscle, bone and other tissues that require its metabolic action. These conditions are also associated with heightened risk for developing type 2 diabetes, glucose intolerance, hypertension, and osteopenia/osteoporosis in older and obese individuals. This is particularly heightened in older women who tend to have increased body fat, are more physically inactive and are at high risk for central obesity and its metabolic consequences of diabetes, hypertension and osteoporosis.

Conditions

  • Vitamin D Status
  • Glucose Tolerance
  • Blood Pressure
  • Bone Mineral Density
  • Hyperlipidemia

Interventions

OTHER

Vitamin D

N/A, frozen specimen study

Sponsors & Collaborators

  • Baltimore VA Medical Center

    lead FED

Principal Investigators

  • Alice S Ryan, PhD · Baltimore VAMC

Eligibility

Min Age
45 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-11-30
Primary Completion
2021-11-30
Completion
2022-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01798030 on ClinicalTrials.gov