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Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies

NCT01776398 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 2000

Last updated 2025-11-14

No results posted yet for this study

Summary

The purpose of this study is to obtain biologic materials from the blood, airways and/or urine of normal individuals and individuals with lung disease. The normal are used to establish a set of normal ranges for various parameters. These provide control information when compared to individuals with various pulmonary diseases, and will help in understanding of the etiology and pathogenesis of various lung diseases. The underlying hypothesis is that the pathologic morphological changes in the airway epithelium must be preceded by changes in the gene expression pattern of the airway epithelium and potentially in macrophages.

Conditions

  • Chronic Obstructive Pulmonary Disease (COPD)
  • Smoking
  • Smoking Cessation
  • Idiopathic Pulmonary Fibrosis (IPF)
  • Rheumatoid Arthritis-Associated Interstitial Lung Disease
  • Scleroderma-Associated Interstitial Lung Disease (SSC-ILD)

Sponsors & Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

    collaborator NIH

  • Boehringer Ingelheim

    collaborator INDUSTRY

  • Cystic Fibrosis Foundation

    collaborator OTHER

  • Weill Medical College of Cornell University

    lead OTHER

Principal Investigators

  • Ronald G. Crystal, M.D. · Weill Medical College of Cornell University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-08-29
Primary Completion
2027-12-31
Completion
2028-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01776398 on ClinicalTrials.gov