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Identification and Validation of Functional Biomarkers for Keratoconus

NCT01746823 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2014-03-06

No results posted yet for this study

Summary

There is currently no medication for containing KC, nor any adequate biomarkers to predict the disease. Furthermore, there is considerable confusion in the field regarding the pathophysiology of the disease and involvement of inflammation. To that end, this study is designed to address some of these questions by determining the proteomic profiles of KC patients with different clinical grades. This relatively large cohort study is expected to yield significant information regarding the molecules that are deregulated during progression of KC and may provide a framework to assign diagnostic biomarkers and therapeutic intervention points.

Conditions

  • Keratoconus

Interventions

DRUG

Cyclosporins

Sponsors & Collaborators

  • Singapore Eye Research Institute

    collaborator OTHER

  • Narayana Nethralaya

    lead OTHER

Principal Investigators

  • Rohit Shetty, MBBS,DNB, FRCS · Narayana Nethralaya

Eligibility

Min Age
10 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-04-30
Primary Completion
2015-12-31
Completion
2015-12-31

Countries

  • India

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01746823 on ClinicalTrials.gov