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AST Combined With 0.05% Cyclosporin Eye Drop Improve Corneal Nerve Density in Patients With SS Dry Eye

NCT06013436 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2023-08-28

No results posted yet for this study

Summary

The objective of the present study was to evaluate the efficacy of autologous serum tears combined with 0.05% cyclosporin eye drop in treating Sjögren's syndrome dry eye and their effect on corneal nerves. We assessed the impact of 12-week AST combined with 0.05% cyclosporin eye drop treatment on signs, symptoms, and sub-basal nerve density (SND) in patients with dry eyes related to Sjogren's syndrome.

Conditions

  • Sjogren's Syndrome
  • Dry Eye
  • Ocular Surface Disease

Interventions

DRUG

Autologous serum tears combined with 0.05% cyclosporin eye drop

All patients administrated autologous serum tears twelve times daily（per hour） and 0.05% cyclosporin eye drop twice times daily in each eye for 12 weeks.

Sponsors & Collaborators

  • Chengdu University of Traditional Chinese Medicine

    lead OTHER

Principal Investigators

  • Jiachun Hu, Resident · Hospital of Chengdu University of Traditional Chinese Medicine

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-06-01
Primary Completion
2023-06-01
Completion
2023-06-01

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06013436 on ClinicalTrials.gov