UK Genetic Prostate Cancer Study: Epidemiology and Molecular Genetics Studies

NCT01737242 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 23826

Last updated 2026-02-04

No results posted yet for this study

Summary

The UKGPCS was set up to find genetic alterations which occur in patients who have prostate cancer.

A man's risk of developing prostate cancer increases if he has a first-degree relative (father or brother) who was diagnosed with prostate cancer at a young age. This is why we are looking for men who are affected at a young age or who have a family history of prostate cancer, since it is more probable that these prostate cancers are due to an inherited genetic cause rather than an environmental cause.

We also ask all men who come to the Royal Marsden Hospital to be treated for prostate cancer if they would like to take part in the study so that we can also look to see if we find genetic alterations in older men, and those who do not have a family history of prostate cancer.

Conditions

Sponsors & Collaborators

  • Cancer Research UK

    collaborator OTHER
  • Royal Marsden NHS Foundation Trust

    collaborator OTHER
  • Institute of Cancer Research, United Kingdom

    lead OTHER

Principal Investigators

  • Rosalind A Eeles, FRCP FRCR · Institute of Cancer Research and Royal Marsden Hospital

Eligibility

Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
1993-01-31
Primary Completion
2023-11-30
Completion
2027-12-31

Countries

  • United Kingdom

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01737242 on ClinicalTrials.gov