MedTrace Logo

Renal Response to Lower Body Negative Pressure in Pre-hypertensive States

NCT01734096 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 78

Last updated 2017-05-24

No results posted yet for this study

Summary

The purpose of this study is to determine whether in pre-hypertensive and hypertensive states such as white coat hypertension, obesity related hypertension or resistant hypertension, renal function is more sensitive to orthostatic stress.

Conditions

Interventions

OTHER

Lower body negative pressure (LBNP)

Lower limbs are put in in LBNP device for one hour (-30 mbar)

DRUG

Candesartan cilexetil

candesartan cilexetil 16 mg once a day for 7 days cross over with placebo in control group, obesisty group and white coat hypertension group

Sponsors & Collaborators

  • Swiss National Science Foundation

    collaborator OTHER

  • PD Dr. Grégoire Wuerzner

    lead OTHER

Principal Investigators

  • Gregoire Wuerzner, MD · Centre Hospitalier Universitaire Vaudois

  • Michel Burnier, MD · Centre Hospitalier Universitaire Vaudois

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-05-31
Primary Completion
2013-04-30
Completion
2016-04-30

Countries

  • Switzerland

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01734096 on ClinicalTrials.gov