Copenhagen Study of Obese Patients With Ischemic Heart Disease Undergoing Low Energy Diet or Interval Training

Summary

The purpose of the study is to make a head-to-head comparison of weight loss and interval training as methods of secondary prevention in overweight patients with ischemic heart disease.

Conditions

• Ischemic Heart Disease
• Obesity

Interventions

OTHER

Interval Training

Interval training (IT) on an exercise bike 3 times a week, for the first 12 weeks, followed by 40 weeks of IT 2 times a week on exercise bike. Each training session consists of active intervals with a total duration of 16 minutes (durations intervals between 1 and 4 minutes) at 90% of maximal heart rate. Active intervals are separated by active pauses at 60% of maximal heart rate.

OTHER

Weight Loss

Low calorie diet approx. 1000 kcal/day for 8 - 10 weeks to obtain a 10 - 15 % weight loss.

Sponsors & Collaborators

• University of Copenhagen

  collaborator OTHER

• Amager Hospital

  collaborator OTHER

• Bispebjerg Hospital

  collaborator OTHER

• Copenhagen University Hospital at Herlev

  collaborator OTHER

• Copenhagen University Hospital, Hvidovre

  collaborator OTHER

• Rigshospitalet, Denmark

  collaborator OTHER

• University of California, Davis

  collaborator OTHER

• Texas A&M University

  collaborator OTHER

• University of Aarhus

  collaborator OTHER

• Eva Prescott

  lead OTHER

Principal Investigators

• Eva Prescott, MD, DMsc · Bispebjerg Hospital

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

45 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2011-09-30

Primary Completion

2014-04-30

Completion

2014-04-30

Countries

• Denmark

Study Locations