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Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function

NCT01723696 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 252

Last updated 2019-04-17

Study results available
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Summary

Vitamin C supplementation (500 mg per day) given to pregnant women who can not quit smoking will improve the pulmonary function tests in their offspring measured at 3 months of age.

Conditions

  • Pulmonary Function; Newborn, Abnormal
  • Infant Wheeze
  • In-utero Nicotine
  • Second Hand Smoke

Interventions

DIETARY_SUPPLEMENT

Vitamin C +prenatal vitamin

Pregnant smoking women will be randomized to daily vitamin C (500 mg) versus daily placebo

DIETARY_SUPPLEMENT

Placebo tablet+prenatal vitamin

Sponsors & Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

    collaborator NIH

  • Office of Dietary Supplements (ODS)

    collaborator NIH

  • Oregon Health and Science University

    lead OTHER

Principal Investigators

  • Cynthia T McEvoy, MD,MCR · Oregon Health and Science University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
15 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-12-31
Primary Completion
2016-04-30
Completion
2017-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01723696 on ClinicalTrials.gov