A Phase 1 Study Evaluating AMG 232 in Advanced Solid Tumors or Multiple Myeloma
NCT01723020 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 107
Last updated 2021-09-02
Summary
First in human, open-label, sequential dose escalation and expansion study of AMG 232 in subjects with advanced solid tumors or multiple myeloma
Conditions
- Advanced Malignancy
- Advanced Solid Tumors
- Cancer
- Oncology
- Oncology Patients
- Tumors
- Glioblastoma
- Multiple Myeloma
Interventions
- DRUG
-
AMG 232
Given an an oral tablet in escalating doses.
Sponsors & Collaborators
-
Kartos Therapeutics, Inc.
lead INDUSTRY
Principal Investigators
-
MD · Amgen
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-12-27
- Primary Completion
- 2017-03-15
- Completion
- 2017-09-25
Countries
- United States
- France
- Netherlands
Study Locations
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