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Ischemia Reperfusion: Prostaglandins and Antioxidants

NCT01666587 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2017-05-12

No results posted yet for this study

Summary

The purposes of this study are two-fold. The first purpose is to determine the effect of taking vitamins on the recovery of an artery (blood vessel) following an induced temporary injury. The second purpose is to determine whether a specific vasodilator is less abundant after the injury and whether this contributes to increased constriction or after the injury. Finally, does vitamin consumption have an effect on the recovery from the injury if one of the substances in the blood that causes vessels to enlarge (dilate) is stopped?

Conditions

  • Ischemic Reperfusion Injury

Interventions

DIETARY_SUPPLEMENT

Antioxidant

DRUG

Prostaglandin inhibitor (Ibuprophen)

Sponsors & Collaborators

  • University of Essex

    lead OTHER

Principal Investigators

  • Mark Rakobowchuk, PhD · Thompson Rivers University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-08-31
Primary Completion
2013-04-30
Completion
2013-08-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01666587 on ClinicalTrials.gov