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Efficacy of Artesunate-Mefloquine Combination Therapy in Trat Province, Thailand

NCT01659281 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 13

Last updated 2012-08-07

No results posted yet for this study

Summary

The main purpose of this study is to compare artesunate-mefloquine combination therapy given for 2 and 3 days at the same total dose for the treatment of uncomplicated falciparum malaria.

Conditions

  • Plasmodium Falciparum Malaria

Interventions

DRUG

Artesunate

6 mg/kg/day for 2 days (total dose 12 mg/kg)

DRUG

Artesunate

4 mg/kg/day for 3 days

DRUG

Mefloquine

15mg/kg at T=0 and 10 mg/kg 6-24 hours later

DRUG

Mefloquine

8 mg/kg daily for 3 days

Sponsors & Collaborators

  • Armed Forces Research Institute of Medical Sciences, Thailand

    lead OTHER_GOV

Principal Investigators

  • Wichai - Satimai, M.D., D.T.M. & H. · Bureau of Vector-Borne Disease, Department of Disease Control, Ministry of Public Health

  • Mark M. Fukuda, M.D. · Dept. of Immunology and Medicine, AFRIMS

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
5 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-09-30
Primary Completion
2008-05-31
Completion
2012-05-31

Countries

  • Thailand

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01659281 on ClinicalTrials.gov