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Genetic Determinants of Congenital Heart Disease Outcomes

NCT01656941 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 250

Last updated 2021-08-10

No results posted yet for this study

Summary

The purpose of this study is to examine the role of genetic variation in the oxidative stress response on critical perioperative and short-term outcomes after neonatal heart surgery. The goals will be to determine 1) if the oxidative stress pathway is an important one for therapeutic intervention in neonates with severe congenital heart defects and 2) if variants in the oxidative response pathway can be used to identify patients at increased risk for adverse outcomes.

Conditions

Sponsors & Collaborators

  • Royal Children's Hospital

    collaborator OTHER

  • Medical University of South Carolina

    collaborator OTHER

  • Emory University

    collaborator OTHER

  • Medical College of Wisconsin

    collaborator OTHER

  • University of Michigan

    lead OTHER

Principal Investigators

  • Nicole S Wilder, MD · University of Michigan

  • Mark W Russell, MD · University of Michigan

Eligibility

Max Age
30 Days
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-03-31
Primary Completion
2017-03-16
Completion
2017-03-16

Countries

  • United States
  • Australia

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01656941 on ClinicalTrials.gov