In-situ Evaluation of Anti-caries Technology
NCT01650493 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 29
Last updated 2024-10-02
Summary
Three toothpastes will be compared, two toothpastes in each subject, to establish whether changes in the depth or area of an artificially created area of tooth decay is the same for each toothpaste.
Conditions
- Caries
Interventions
- DEVICE
-
Clinpro 5000
Dentrifice containing 950ppm fluoride
- DEVICE
-
MI Paste Plus
Dentrifice containing 950ppm fluoride
- DEVICE
-
Tom's of Maine
Dentrifice that is fluoride free
Sponsors & Collaborators
-
University of Iowa
collaborator OTHER -
3M
collaborator INDUSTRY -
Solventum US LLC
lead INDUSTRY
Principal Investigators
-
Clark Stanford, PhD · Dows Institute for Dental Research
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2012-06-30
- Primary Completion
- 2013-05-31
- Completion
- 2013-07-31
Countries
- United States
Study Locations
More Related Trials
-
In Situ Caries of Fluoride Toothpastes
NCT00708123 ·Status: COMPLETED ·Phase: PHASE3
-
A Clinical Study to Evaluate Experimental Children's Toothpastes in an In-Situ Caries Model
NCT01607411 ·Status: COMPLETED ·Phase: PHASE3
-
MI Varnish and MI Paste Plus in a Caries Prevention and Remineralization Study
NCT02424097 ·Status: COMPLETED ·Phase: PHASE4
-
A Phase 2 Study to Evaluate the Microbiology, Safety and Tolerability of C16G2 Varnish and Strip in Adolescent and Adult Subjects
NCT03196219 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of Dentifrice Formulations to Remineralize Enamel and Dentine Subsurface Lesions in a Double-Blind In-Situ Clinical Trial
NCT06140745 ·Status: COMPLETED ·Phase: NA
-
A Study to Evaluate the Safety and Microbiology of C16G2 Varnish Administered in Multiple Doses to Dental Subjects
NCT03004365 ·Status: COMPLETED ·Phase: PHASE2
-
The Purpose of This Research Study is to Compare the Effectiveness of a Non-fluoride Whitening Toothpaste (Test) to That of a Non-whitening Fluoride Toothpaste (Negative Control) in Improving Tooth Whiteness (Removal of Extrinsic Stains) Over 8 Weeks of Unsupervised Use.
NCT07219342 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
The Effect of Experimental Dentifrices on Remineralization of Caries Lesions In-situ
NCT02195583 ·Status: COMPLETED ·Phase: NA
-
Clinical Study to Evaluate the Anti-cavity Efficacy of Three Dentifrices: An In Situ Model
NCT07134231 ·Status: COMPLETED ·Phase: PHASE3
-
In Situ Caries Model of Fluoride Toothpastes
NCT01005966 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of the Anti-cavity Efficacy of Three Dentifrices Using an Intra-oral Enamel Demineralization - Remineralization In-Situ Model
NCT06732518 ·Status: COMPLETED ·Phase: PHASE3
-
3M Oral Rinse Incidence and Patient Acceptance of Sloughing When Used With Sodium Lauryl Sulfate (SLS) Toothpastes
NCT04601103 ·Status: TERMINATED ·Phase: NA
-
Evaluation of a Test Mouthwash and Dentifrice Regimen in an In-situ Model of Dental Erosion
NCT01128972 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of Efficacy of Experimental Gel to Foam Dentifrices in Dental Erosion
NCT01657903 ·Status: COMPLETED ·Phase: NA
-
Phase 2, Safety & Microbiology Study of C16G2 in Multiple Oral Gel &/or Mouth Rinse Doses to Healthy Adults
NCT02044081 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety Evaluation of Anti-Caries Varnish
NCT04947527 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Dentifrice Usage Regime on Delivery and Efficacy of Fluoride
NCT01563172 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of Virtually Supervised Mouthwash and Interdental Brushes
NCT05756673 ·Status: COMPLETED ·Phase: PHASE4
-
In Situ Caries Efficacy of Fluoride Toothpastes
NCT00708097 ·Status: COMPLETED ·Phase: PHASE3
-
Enamel Remineralization Potential of Dentifrices in Situ
NCT01128946 ·Status: COMPLETED ·Phase: PHASE4
-
Study to Evaluate the Safety and Microbiology of C16G2 in Adolescent and Adult Dental Subjects
NCT02509845 ·Status: COMPLETED ·Phase: PHASE2
-
The Clinical of Stannous Fluoride Toothpaste and a Newly Designed Toothbrush Compared to Colgate Cavity Protection Toothpaste and a Regular Toothbrush in Reducing Plaque and Gingivitis.
NCT06427499 ·Status: COMPLETED ·Phase: PHASE3
-
Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis.
NCT06244303 ·Status: COMPLETED ·Phase: PHASE3
-
Experimental Dentifrice Remineralization/Fluoride Uptake in an in Situ Model
NCT00752089 ·Status: COMPLETED ·Phase: PHASE2
-
Fluoride in Saliva After Use of Fluoride Toothpastes Followed by Fluoride Mouthrinses
NCT05601154 ·Status: COMPLETED ·Phase: EARLY_PHASE1