NUtriGenomic Analysis in Twins

Summary

This is an intervention study in healthy adult twins with the aim to investigate the genetic determination of metabolic responses towards an isocaloric high carbohydrate, low fat diet versus an isocaloric low carbohydrate, high fat diet.

Conditions

• Metabolic Response to Dietary Modification

Interventions

OTHER

Isocaloric high carbohydrate diet intervention

Time of 6 week, the last 6 days are standardized

OTHER

Isocaloric high fat diet intervention

Time of 6 weeks; the first and the last 6 days are standardized

Sponsors & Collaborators

• German Federal Ministry of Education and Research

  collaborator OTHER_GOV

• Charite University, Berlin, Germany

  collaborator OTHER

• Ernst von Bergmann Hospital

  collaborator OTHER

• University Hospital Tuebingen

  collaborator OTHER

• University of Southern California

  collaborator OTHER

• Ludwig-Maximilians - University of Munich

  collaborator OTHER

• Heidelberg University

  collaborator OTHER

• HealthTwist GmbH, Berlin, Germany

  collaborator UNKNOWN

• Max-Planck Institute of Molecular Cell Biology and Genetics

  collaborator OTHER

• Helmholtz Center Munich

  collaborator UNKNOWN

• German Institute of Human Nutrition

  lead OTHER

Principal Investigators

• Andreas FH Pfeiffer, Prof · German Institute of Human Nutrition Potsdam-Rehbruecke

Study Design

Allocation

NA

Purpose

BASIC_SCIENCE

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2009-09-30

Primary Completion

2010-01-31

Completion

2012-09-30

Countries

• Germany