Effect of Bright Light on Mood and Sleep in Parkinson's Disease

Summary

The purpose of this clinical trial is to investigate whether light therapy is a suitable treatment option for depression and insomnia in Parkinson's disease.

Conditions

• Parkinson's Disease
• Depression

Interventions

DEVICE

light therapy 30 min morning and evening, three months

Light from a commercially available table-mounted lightbox (Brazil, Lumie, Cambridge UK) \[dimensions 50.2 x 32 x 15.4 cm\] equipped with 3x36W Fluorescent bulbs (Osram 954), reflectors and a diffuser screen providing 10,000 lux at 30 cm eye level distance. therapy consists of 30 minutes light exposure in the morning and evening during 3 months.

DEVICE

light therapy 30 min morning and evening, three months

200 lux light from a commercially available table-mounted lightbox (Brazil, Lumie, Cambridge UK) \[dimensions 50.2 x 32 x 15.4 cm\] To lower the intensity to 200 lux the bulbs are enwrapped with one layer of L299s neutral density filter (LEE Filters, Andover, UK). Therapy consists of 30 minutes light exposure in the morning and evening during 3 months.

Sponsors & Collaborators

• International Parkinson Foundation ('IPF'), Hoofddorp, The Netherlands

  collaborator UNKNOWN

• Parkinsonvereniging, Bunnik, the Netherlands

  collaborator UNKNOWN

• Netherlands Brain Foundation

  collaborator OTHER

• Netherlands Institute for Neurosciences, Amsterdam, The Netherlands

  collaborator UNKNOWN

• GGZ inGeest

  collaborator OTHER

• Amsterdam UMC, location VUmc

  lead OTHER

Principal Investigators

• Odile A van den Heuvel, MD PHD · Amsterdam UMC, location VUmc

• Ysbrand D van der Werf, PHD · Amsterdam UMC, location VUmc

• Jan H Smit, PHD · Amsterdam UMC, location VUmc

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Model

PARALLEL

Eligibility

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2012-05-31

Primary Completion

2017-02-28

Completion

2017-02-28

Countries

• Netherlands

Study Locations