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Serial Hybrid Atrial Fibrillation Ablation

NCT01582828 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2024-11-22

No results posted yet for this study

Summary

Treatment of (long-standing) persistent atrial fibrillation (AF) remains cumbersome and the surgical (epicardial) approach seems to be the most effective. Still, however a significant amount of failures exist which is mostly due to incompleteness of the surgical ablation lines. Checking, and if necessary additional ablation, of these lines afterwards endocardially by the cardiologist (the so-called serial hybrid approach) could overcome this problem.

Conditions

Interventions

PROCEDURE

Epicardial (surgical) ablation

* Pulmonary vein isolation with bipolar clamps and bipolar box lesion * Epicardial atrial appendage closure

PROCEDURE

Hybrid

Epicardial (surgical) ablation * Pulmonary vein isolation with bipolar clamps and bipolar box lesion * Epicardial atrial appendage closure Endocardial assessment after 6-8 weeks, checking for isolation and if necessary touch up by RF ablation

Sponsors & Collaborators

  • Medisch Spectrum Twente

    lead OTHER

Principal Investigators

  • Jurren van Opstal, MD PhD · Medisch Spectrum Twente

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-08-31
Primary Completion
2016-12-31
Completion
2017-12-31

Countries

  • Netherlands

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01582828 on ClinicalTrials.gov