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Studying Genes Using Cord Blood and Placenta Samples From Relatively Healthy Newborns and Samples From Younger Patients With Wilms Tumor

NCT01576211 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2016-05-18

No results posted yet for this study

Summary

RATIONALE: Studying samples of blood and tissue from newborns and from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.

PURPOSE: This research trial studies cord blood and placenta tissue from newborns, and tumor tissue samples from patients with Wilms tumor.

Conditions

Interventions

GENETIC

DNA methylation analysis

GENETIC

RNA analysis

GENETIC

allele-specific oligonucleotide real-time quantitative polymerase chain reaction

GENETIC

gene expression analysis

GENETIC

nucleic acid sequencing

GENETIC

polymorphism analysis

OTHER

laboratory biomarker analysis

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH

  • Children's Oncology Group

    lead NETWORK

Principal Investigators

  • Karin Michels, MD, PhD · Dana-Farber/Brigham and Women's Cancer Center

Eligibility

Max Age
21 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-04-30
Primary Completion
2016-05-31

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01576211 on ClinicalTrials.gov