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Biomarkers in Tissue Samples From Patients With High-Risk Wilms Tumor

NCT01118078 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 185

Last updated 2016-05-19

No results posted yet for this study

Summary

This research study is studying biomarkers in tissue samples from patients with high-risk Wilms tumor. Studying samples of tissue from patients with cancer in the laboratory may help doctors to learn more about changes that occur in DNA and identify biomarkers related to cancer.

Conditions

  • Clear Cell Sarcoma of the Kidney
  • Recurrent Wilms Tumor and Other Childhood Kidney Tumors
  • Rhabdoid Tumor of the Kidney
  • Stage I Wilms Tumor
  • Stage II Wilms Tumor
  • Stage III Wilms Tumor
  • Stage IV Wilms Tumor
  • Stage V Wilms Tumor

Interventions

GENETIC

DNA methylation analysis

Undergo DNA methylation analysis

GENETIC

gene expression analysis

Undergo gene expression analysis

GENETIC

microarray analysis

Undergo microarray analysis

GENETIC

reverse transcriptase-polymerase chain reaction

Undergo RT-PCR

OTHER

diagnostic laboratory biomarker analysis

Correlative studies

Sponsors & Collaborators

  • National Cancer Institute (NCI)

    collaborator NIH

  • Children's Oncology Group

    lead NETWORK

Principal Investigators

  • Elizabeth Perlman, MD · Children's Oncology Group

Eligibility

Max Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-05-31
Primary Completion
2016-05-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01118078 on ClinicalTrials.gov