Efficacy Of PF-05089771 In Treating Postoperative Dental Pain
NCT01529346 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 235
Last updated 2018-06-01
Summary
The objective of this study is to evaluate the overall pain relief of a single dose of PF-05089771 against placebo following third molar extraction.
Conditions
- Postoperative Dental Pain
Interventions
- DRUG
-
PF-05089771
A single dose of PF-05089771 1600 mg oral solution administered once to the subject on Day 1 postoperatively
- OTHER
-
Placebo
Placebo tablets for ibuprofen: 2 X 200 mg placebo tablets administered orally once to the subject on Day 1 postoperatively
- DRUG
-
PF-05089771
A single dose of PF-05089771 450 mg oral solution administered once to the subject on Day 1 postoperatively
- OTHER
-
Placebo
Placebo tablets for ibuprofen: 2 X 200 mg placebo tablets administered orally once to the subject on Day 1 postoperatively
- DRUG
-
PF-05089771
A single dose of PF-05089771 150 mg oral solution administered once to the subject on Day 1 postoperatively
- OTHER
-
Placebo
Placebo tablets for ibuprofen: 2 X 200 mg placebo tablets administered orally once to the subject on Day 1 postoperatively
- DRUG
-
2 X 200 mg tablets of ibuprofen administered orally once to the subject on Day 1 postoperatively
- OTHER
-
Placebo
Placebo solution for PF-05089771: A single dose of Placebo solution administered once to the subject on Day 1 postoperatively
- OTHER
-
Placebo
Placebo solution for PF-05089771:A single dose of Placebo solution administered once to the subject on Day 1 postoperatively
- OTHER
-
Placebo
Placebo tablets for Ibuprofen: 2 X 200 mg placebo tablets administered orally once to the subject on Day 1 postoperatively
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Pfizer CT.gov Call Center · Pfizer
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-12-12
- Primary Completion
- 2012-06-25
- Completion
- 2012-06-25
Countries
- United States
Study Locations
More Related Trials
-
A Study of Ibuprofen (IBU) 250mg/APAP 500mg In The Treatment Of Post-Surgical Dental Pain
NCT02837952 ·Status: COMPLETED ·Phase: PHASE3
-
To Evaluate the Safety, Tolerability and Analgesic Efficacy of SAF312 in Postoperative Dental Pain Patients
NCT00986882 ·Status: COMPLETED ·Phase: PHASE2
-
Ibuprofen, Paracetamol Versus Placebo on Pain During Local Anesthetic Injection (RCT)
NCT03184649 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Efficacy of Ibuprofen Chronotherapy in Healing After Surgical Extraction of the Mandibular Third Molar
NCT03789058 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Efficacy of 300 mg Ibuprofen Prolonged-Release Tablets for the Treatment of Pain After Surgical Removal of Impacted Third Molars
NCT03785756 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Preoperative Oral Ibuprofen on Anesthetic Efficacy of Inferior Alveolar Nerve Block With Supplemental Buccal and Lingual Infiltrations Using Articaine in Mandibular Molar Teeth With Irreversible Pulpitis
NCT05927922 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-190)(COMPLETED)
NCT00092339 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-181)(COMPLETED)
NCT00092300 ·Status: COMPLETED ·Phase: PHASE3
-
Methodological Validation of Ibuprofen Verses Placebo for Post Operative Pain After Third Molar Extraction Surgery
NCT02096926 ·Status: COMPLETED ·Phase: PHASE4
-
Towards Predicting the Analgesic Response to Ibuprofen Following Third-molar Extraction
NCT03893175 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Long-Acting Acetaminophen in Postoperative Dental Pain
NCT01960114 ·Status: COMPLETED ·Phase: PHASE2
-
An Analgesic Study to of V117957 for the Treatment of Postsurgical Pain Due to Third Molar Extraction
NCT01900795 ·Status: TERMINATED ·Phase: PHASE2
-
Variability in Analgesic Response to Ibuprofen
NCT06539741 ·Status: RECRUITING
-
Pain Control Following Third Molar Surgery
NCT06514222 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
Ibuprofen Liquid Capsules 2 x 200 mg Efficacy and PK/PD Study in Surgical Removal of Impacted Third Molars
NCT05484401 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Assess the Efficacy and Tolerability of Diclofenac Potassium Soft Gelatin Capsules Compared With Ibuprofen Tablets in Patients With Moderate to Severe Postoperative Dental Pain
NCT02476422 ·Status: COMPLETED ·Phase: PHASE3
-
Ibuprofen Extended-Release Dental Pain Study
NCT00707057 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Acetaminophen (ACM) in Post-operative Dental Pain
NCT02735122 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Efficacy of MK0719 in the Prevention of Postoperative Dental Pain (0719-002)
NCT00424424 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Acetaminophen (ACE) in Post-operative Dental Pain
NCT02320708 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluating the Combined Effect of Oral Premedications on Inferior Alveolar Nerve Block Effectiveness
NCT07146997 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-183)
NCT00092326 ·Status: COMPLETED ·Phase: PHASE3
-
Etoricoxib Versus Ibuprofen in Third Molar Extraction Pain
NCT00855777 ·Status: UNKNOWN ·Phase: PHASE4
-
Analgesic Efficacy and Safety of ADL5859 in Subjects With Acute Dental Pain After Third Molar Extraction
NCT00993863 ·Status: COMPLETED ·Phase: PHASE2
-
Anti Inflammatory and Analgesic Effect of Ginger Powder in Dental Pain Model
NCT01429935 ·Status: UNKNOWN ·Phase: PHASE2