LIFE Cancer Survivorship Database for Pediatric Cancer
NCT01518400 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 5000
Last updated 2022-06-13
Summary
The purpose of this study is to develop a mechanism for utilizing the comprehensive clinical database of childhood cancer survivors at Childrens Hospital Los Angeles (CHLA) for research purposes. Using clinical information obtained from follow-up visits of childhood cancer survivors, the database will focus on interventions to improve health status and health-related quality of life in childhood cancer survivors. This study allows for establishment and analyses of a research database for LIFE survivors by the investigators listed herein. Over the last three decades, there has been marked improvement in survival following childhood cancer, with 5-year survival rates now approaching 80%. However, the use of cancer therapy at an early age can result in complications that may not be apparent until years later as the child matures. These resulting complications, called late effects, are principally related to the specific therapy employed and the age of the child at the time the therapy was administered. Late effects may affect virtually every body system and substantially impair quality of life. As many as two-thirds of childhood cancer survivors develop at least one late effect as a result of treatment, and approximately one-third have a late effect classified as severe or life threatening.
Conditions
- Pediatric Cancer
Sponsors & Collaborators
-
Children's Hospital Los Angeles
lead OTHER
Principal Investigators
-
David Freyer, DO, MS · Children's Hospital Los Angeles
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-02-28
- Primary Completion
- 2050-01-31
- Completion
- 2050-12-31
Countries
- United States
Study Locations
More Related Trials
-
Establishment of a Lifetime of Cohort of Adults Surviving Childhood Cancer
NCT00760656 ·Status: RECRUITING
-
Evaluating Supportive Care for Children With Cancer: A Multi-Institutional Survey Study of Pediatric Oncology Patients and Parents
NCT01273194 ·Status: COMPLETED
-
Beat Childhood Cancer Specimen Banking and Data Registry
NCT04715178 ·Status: RECRUITING
-
Long-Term Effects of Treatment in Patients Previously Treated for Childhood Hodgkin's Lymphoma
NCT00091091 ·Status: COMPLETED
-
Therapy for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia
NCT00137111 ·Status: COMPLETED ·Phase: PHASE3
-
Radiation Therapy and the Natural History of Childhood Cancers
NCT00064883 ·Status: COMPLETED
-
Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma
NCT03117751 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3
-
Generating Novel Translational and Therapeutic Strategies Based on a Multicenter, Pediatric and AYA Evolutionary Tumor Board (pedsETB)
NCT06423950 ·Status: RECRUITING
-
Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma
NCT05535166 ·Status: RECRUITING ·Phase: PHASE2
-
Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma
NCT00057811 ·Status: COMPLETED ·Phase: PHASE2
-
Validation Study of Pediatric Patient-Reported Outcomes
NCT03229837 ·Status: COMPLETED
-
Late Effects of Treatment for Sarcomas in Children
NCT00006515 ·Status: COMPLETED
-
A Longitudinal Assessment of Frailty in Young Adult Survivors of Childhood Cancer
NCT02256137 ·Status: ACTIVE_NOT_RECRUITING
-
Molecular-Guided Therapy for Childhood Cancer
NCT02162732 ·Status: COMPLETED ·Phase: NA
-
Financial Distress During Treatment for Pediatric Acute Lymphoblastic Leukemia in the United States
NCT04928599 ·Status: ACTIVE_NOT_RECRUITING
-
Feasibility of Screening for Early Late Effects of Contemporary Therapy in High-Risk Neuroblastoma Survivors
NCT06480526 ·Status: ACTIVE_NOT_RECRUITING
-
Pilot Prospective Study for PET-CT Imaging in Participants With Relapsed/Refractory Acute Leukemias
NCT05969002 ·Status: COMPLETED
-
Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia
NCT02303821 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia
NCT00002816 ·Status: COMPLETED ·Phase: PHASE3
-
Integrative Molecular Analysis of Individual Radiosensitivity in Pediatric Oncology
NCT06033183 ·Status: RECRUITING ·Phase: NA
-
Early Enteral Tube Feedings in Children Receiving Chemo for AML/MDS & High Risk Solid Tumors
NCT00624962 ·Status: WITHDRAWN ·Phase: NA
-
Carboplatin and Irinotecan in Treating Children With Refractory Solid Tumors
NCT00024284 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment
NCT02932280 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Combination Chemotherapy in Treating Children With Progressive Brain Tumors
NCT00002944 ·Status: COMPLETED ·Phase: PHASE3
-
Circulating microRNAs as Disease Markers in Pediatric Cancers
NCT01541800 ·Status: COMPLETED