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Comparing Nitrous Oxide and Carbon Dioxide for Laparoscopic Cholecystectomy

NCT01512511 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2012-01-19

No results posted yet for this study

Summary

There is no general agreement about the ideal gas for pneumoperitoneum. CO2, now in common use, has not compared to N2O sufficiently to disclose which one has minimal "physiological" invasiveness characters. Assigned randomly to carbon dioxide or nitrous oxide group, the hemodynamic and respiratory parameters (heart rate, mean arterial blood pressure, end-tidal CO2, minute ventilation, and O2 saturation) before pneumoperitoneum and during it were recorded. Pain, as perceived by patients, is measured 2, 4 and 24 hours after the procedure by visual analogue scale. Vomiting and use of analgesics and antiemetics were recorded and compared.

Conditions

  • Pneumoperitoneum

Interventions

PROCEDURE

nitrous oxide use for pneumoperitoneum creation

use nitrous oxide for create pneumoperitoneum in laparoscopic cholecystectomy

Sponsors & Collaborators

  • Ahvaz Jundishapur University of Medical Sciences

    lead OTHER

Principal Investigators

  • Mehdi Asgari, PhD · Ahvaz Jundishapur University of Medical Sciences

Study Design

Allocation
RANDOMIZED
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-11-30
Primary Completion
2011-03-31
Completion
2011-04-30

Countries

  • Iran

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01512511 on ClinicalTrials.gov