Impact of Isoflurane and Sevoflurane on Oxidative Stress in Patients Undergoing Laparoscopic Cholecystectomy
NCT07152912 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80
Last updated 2025-09-05
Summary
The primary aim of this work is to assess the impact of exposure to isoflurane or sevoflurane as an inhalation anesthetic on the oxidative stress and inflammatory conditions in patients undergoing elective moderate invasive surgery (laparoscopic cholecystectomy).
Conditions
- Isoflurane
- Sevoflurane
- Oxidative Stress
- Laparoscopic Cholecystectomy
Interventions
- DRUG
-
Isoflurane
Patients will receive general anesthesia and maintenance by isoflurane.
- DRUG
-
Sevoflurane
Patients will receive general anesthesia and maintenance by sevoflurane.
Sponsors & Collaborators
-
Ain Shams University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 20 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-09-04
- Primary Completion
- 2026-03-01
- Completion
- 2026-03-01
Countries
- Egypt
Study Locations
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