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Comparison of Effects of PEEP Levels on Respiratory Mechanics in Patients Undergoing Laparoscopic Cholecystectomy

NCT02439801 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 75

Last updated 2015-05-12

No results posted yet for this study

Summary

Laparoscopic cholecystectomy is accepted as gold standard in the management of cholelithiasis. Although laparoscopic procedures have many advantages,intra-abdominal CO2 insufflation can cause decreased lung volumes and compliance, increased airway resistance and impaired ventilation-perfusion ratio. In this study, investigators aim to investigate effects of intra-operative PEEP treatment at 3 distinct levels on respiratory dynamics and elimination time of volatile anesthetic agent.

Conditions

  • Respiratory System Abnormalities

Interventions

PROCEDURE

PEEP 0

0 cmH2O positive end expiratory pressure

PROCEDURE

PEEP 5

5 cmH2O positive end expiratory pressure

PROCEDURE

PEEP 8

8 cmH2O positive end expiratory pressure

Sponsors & Collaborators

  • Umraniye Education and Research Hospital

    lead OTHER_GOV

Principal Investigators

  • Nurten Bakan, MD · Unraniye training hospital

Eligibility

Min Age
30 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-03-31
Primary Completion
2015-05-31
Completion
2015-05-31

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02439801 on ClinicalTrials.gov