MedTrace Logo

Analgesic Effect of Gabapentin in Total Knee Arthroplasty (TKA)

NCT01507363 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 300

Last updated 2014-04-11

No results posted yet for this study

Summary

Pain is a major problem after TKA. Gabapentin may reduce acute postoperative pain. The investigators therefore investigate the effect of Gabapentin as a perioperative analgesic.

Conditions

  • Postoperative Pain
  • Postoperative Sedation

Interventions

DRUG

Gabapentin

Tables with Gabapentin (1300 mg/ day) for 7 days, starting on the day of surgery

DRUG

Gabapentin

Tables with Gabapentin (900 mg/day) for 7 days, starting on the day of surgery

DRUG

Placebo

Placebo tablets for 7 days, starting on the day of surgery

Sponsors & Collaborators

  • Lundbeck Foundation

    collaborator OTHER

  • Hvidovre University Hospital

    lead OTHER

Principal Investigators

  • Torben B Hansen B Hansen, MD · Regionshospitalet Holstebro

  • Henrik Kehlet, MD · Rigshospitalet, Denmark

  • Jørgen B Dahl, MD · Rigshospitalet, Denmark

  • Per W Kristensen, MD · Vejle Sygehus

  • Henrik Husted, MD · Hvidovre University Hospital

  • Søren Solgaard, MD · Gentofte Hospital

  • Mogens B Laursen, MD, Phd. · Aalborg Sygehus

  • Lars Hansen, MD · Esbjerg Sygehus

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
50 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-01-31
Primary Completion
2013-11-30
Completion
2013-11-30

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01507363 on ClinicalTrials.gov